Simple Computational Models can Help Predict Post-Traumatic Osteoarthritis
Knee joint injuries, such as ligament rupture, are common in athletes. As the intact joint ligaments offer a precondition for joint stability, ligament injuries are often surgically reconstructed. However, in many cases these injuries or surgeries can lead to post-traumatic osteoarthritis. The articular cartilage, which serves to provide frictionless contact between bones, wears out completely, causing severe joint pain, lack of mobility and even social isolation.
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Virtual Patients and In Silico Clinical Studies Improve Blue Light Treatment for Psoriasis
A new study supports the use of virtual patients and in silico clinical studies to evaluate the effectiveness of blue light to reduce the symptoms of psoriasis. Researchers also demonstrated that this in silico approach can be used to improve the treatment response of patients with psoriasis to blue light by modifying the settings of the therapeutic protocol, as reported in the study published in Systems Medicine, an open access journal from Mary Ann Liebert, Inc., publishers.
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Successful First Trial for Dizziness Monitoring Device
A ground-breaking device to help patients with dizziness problems has moved a step forward following a successful research study. Researchers from UEA and the Norfolk and Norwich University Hospital (NNUH) have published the results of the biggest collection of continuous eye movement data after testing the effectiveness of a wearable diagnostic headset.
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Clinical trials are a critical tool for getting new treatments to people who need them, but research shows that difficulty finding the right volunteer subjects can undermine the effectiveness of these studies. Researchers at Cincinnati Children's Hospital Medical Center designed and tested a new computerized solution that used artificial intelligence (AI) to effectively identify eligible subjects from Electronic Health Records (EHRs),
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Cardio-Respiratory Synchronization may Represent a New Measure of Health and Fitness
Researchers from the School of Engineering at the University of Warwick have managed to expand the knowledge of the cardio-respiratory system after conducting an experiment measuring heart rate during fast-paced breathing. Published in Scientific Reports, the paper 'Control of heart rate through guided high-rate breathing' shows how researchers found it is possible to reliably observe a one-to-one relationship between heart beats and breaths, when breathing is controlled at a speed exceeding resting heart rate.
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Review Evaluates How AI could Boost the Success of Clinical Trials
Big pharma and other drug developers are grappling with a dilemma: the era of blockbuster drugs is coming to an end. At the same time, adding new drugs to their portfolios is slow and expensive. It takes on average 10-15 years and $1.5-2B to get a new drug to market; approximately half of this time and investment is devoted to clinical trials.
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Are Fertility Apps Useful?
For many women of reproductive age, the most common way of assessing their menstrual health and fertility means regular visits to a gynecologist or another clinician. When it comes to evaluating changes in fertility, menstrual health, and quality of life, these visits typically rely on remembering, which can lead to significant inaccuracies in evaluation.
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