The challenge is to make Europe the best place in the world for collaborative research and innovation on future and emerging technologies that will renew the basis for future European competitiveness and growth, and that will make a difference for society in the decades to come. The successful exploration of new foundations for radically new future technologies requires supporting a large set of early stage, high risk visionary science and technology projects to investigate new ideas. Here agile, risk-friendly and highly interdisciplinary research approaches are needed with collaborations that are open to all sciences and disciplines and that dissolve the traditional boundaries between them. Several activities on scaling up of digital innovation for active and healthy ageing are currently pursued by the Commission in cooperation with a large number of different stakeholder groups and partner organisations. A coordination and support action is needed to promote the effective uptake and impact of these activities and to leverage additional investments by mobilising other national and regional programmes together with private investments. The challenge is to help overcome the current gaps in exploitation of promising research results in ICT for Health, Well-being and Ageing well and to stimulate increased availability and market uptake of relevant ICT products and services This concerns both interoperable and secure eHealth solutions for consumers and institutional healthcare delivery building on standards and new ICT solutions and innovation ecosystems for ageing well building on open software platforms, in order to deliver new and more efficient care to European citizens and respond to new market opportunities for SMEs. 
Patient stratification aims at grouping patients into disease sub-groups, where the specific pathological processes involved are better defined (clinical/molecular phenotypes). This will lead to the development of targeted therapies, optimizing the intervention to individual patients, thus achieving greater success in treating or curing the patient.