Patient stratification aims at grouping patients into disease sub-groups, where the specific pathological processes involved are better defined (clinical/molecular phenotypes). This will lead to the development of targeted therapies, optimizing the intervention to individual patients, thus achieving greater success in treating or curing the patient.
Proposals should deliver novel concepts for disease-mechanism based patient stratification to address the needs for stratified or personalised therapeutic interventions. The proposals should integrate multidimensional and longitudinal data and harness the power of -omics, including pharmacogenomics, systems biomedicine approaches, network analysis and of computational modelling. The new concepts of stratification should be validated in pre-clinical and clinical studies taking into account sex and gender differences. Applicants are encouraged to actively involve patient associations. The proposals should consider regulatory aspects of clinical practice and commercialisation opportunities. Proposals should focus on complex diseases having high prevalence and high economic impact.
The Commission considers that proposals requesting a contribution from the EU of between EUR 4 and 6 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.
Deadline: 04 October 2016 17:00:00
Deadline Model: two-stage
Type of action: RIA Research and Innovation action.
For topic conditions, documents and submission service, please visit:
http://ec.europa.eu/research/participants/portal/desktop/en/opportunities/h2020/topics/23059-sc1-pm-02-2017.html
PS: Find your partners or consortia preparing a project proposal
If you are working on Horizon 2020 research project proposals and you would be interested in a SME partner from Germany, please contact us, we are happy to share our experience, expertise and knowledge. If you need help to identify a potential partner with particular competences, facilities or experience, please join and explore our project, (HEALTH IT) SPACE, at www.healthitspace.eu.