The challenge is to make Europe the best place in the world for collaborative research and innovation on future and emerging technologies that will renew the basis for future European competitiveness and growth, and that will make a difference for society in the decades to come.

The successful exploration of new foundations for radically new future technologies requires supporting a large set of early stage, high risk visionary science and technology projects to investigate new ideas. Here agile, risk-friendly and highly interdisciplinary research approaches are needed with collaborations that are open to all sciences and disciplines and that dissolve the traditional boundaries between them.

Several activities on scaling up of digital innovation for active and healthy ageing are currently pursued by the Commission in cooperation with a large number of different stakeholder groups and partner organisations. A coordination and support action is needed to promote the effective uptake and impact of these activities and to leverage additional investments by mobilising other national and regional programmes together with private investments.

The challenge is to help overcome the current gaps in exploitation of promising research results in ICT for Health, Well-being and Ageing well and to stimulate increased availability and market uptake of relevant ICT products and services This concerns both interoperable and secure eHealth solutions for consumers and institutional healthcare delivery building on standards and new ICT solutions and innovation ecosystems for ageing well building on open software platforms, in order to deliver new and more efficient care to European citizens and respond to new market opportunities for SMEs.

Patient stratification aims at grouping patients into disease sub-groups, where the specific pathological processes involved are better defined (clinical/molecular phenotypes). This will lead to the development of targeted therapies, optimizing the intervention to individual patients, thus achieving greater success in treating or curing the patient.

Proposals will develop innovative in-silico trials for designing, developing and assessing drugs, radiation and other biomedical and bioactive products. They will build on comprehensive biological and biomedical knowledge management and advanced modelling paradigms in order to be able to simulate the individual human physiology and physiopathology at the

Proposals should aim at the development of new integrative dynamic computer-models and simulation systems of acceptable validity, with the potential to being reused, build on open service platforms and with application in well-being, health and disease. The projects have to support computer modelling and simulations able to aggregate various information sets

This SME-led pilot is an innovation capacity building action to provide at European level a grant to visionary SMEs which have experienced difficulty in recruiting the relevant skills nationally. SMEs are supported to employ a highly-skilled experienced researcher e.g an 'associate' for one year from September 2017.

The call will address joint research and innovation proposals for developing and demonstrating advanced ICT Robotics based solutions for extending active and healthy ageing in daily life. Proposals should build on advances in this domain, and should combine multi-disciplinary research involving behavioural, sociological, health and other relevant disciplines.

Proposals should develop population-oriented primary prevention interventions to promote mental well-being of young people and assess them for their effectiveness. The interventions should build on but may go beyond existing state-of-the art knowledge on biological, psychological and social determinants of mental well-being such as societal, cultural, work life, lifestyle, epidemiological, economic and environmental perspectives.