Research

A Step Forward in Building Functional Human Tissues

Toward the ultimate goal of engineering human tissues and organs that can mimic native function for use in drug screening, disease modeling, and regenerative medicine, a Wyss Institute team led by Core Faculty member Jennifer Lewis, Sc.D., has made another foundational advance using three-dimensional (3D) bioprinting. This work builds upon their demonstrated ability to bioprint tissue constructs composed of multiple types of living cells patterned alongside a vascular network in an extracellular matrix.

Mapping the 'Dark Matter' of Human DNA

Researchers from ERIBA, Radboud UMC, XJTU, Saarland University, CWI and UMC Utrecht have made a big step towards a better understanding of the human genome. By identifying large DNA variants in 250 Dutch families, the researchers have clarified part of the "dark matter", the great unknown, of the human genome. These new data enable researchers from all over the world to study the DNA variants and use the results to better understand genetic diseases.

Imaging Stroke Risk in 4D

Affecting 33.5 million patients worldwide, atrial fibrillation is the most common form of cardiac arrhythmia. As if having an irregular heart beat wasn't troubling enough, patients with atrial fibrillation are also much more likely to have a stroke. "Atrial fibrillation is thought to be responsible for 20 to 30 percent of all strokes in the United States," said Northwestern University's Michael Markl, the Lester B. and Frances T. Knight Professor of Cardiac Imaging. "While atrial fibrillation is easy to detect and diagnose, it's not easy to predict who will suffer a stroke because of it."

Using Twitter as a Data Source for Studying Public Communication about Cardiovascular Health

Person-to-person communication is one of the most persuasive ways people deliver and receive information. Until recently, this communication was impossible to collect and study. Now, social media networks, such as Twitter, allow researchers to systematically witness public communication about health, including cardiovascular disease. Twitter is used by more than 300 million people who have generated several billion Tweets, yet little work has focused on the potential applications of these data for studying public attitudes and behaviors associated with cardiovascular health.

Video Gamers Outdo Scientists in Contest to Discover Protein's Shape

Foldit is developed by the Center for Game Science at University of Washington in collaboration with UW Department of Biochemistry.

Gamers playing the popular online puzzle game Foldit beat scientists, college students and computer algorithms in a contest to see who could identify a particular protein's shape. The study findings have implications for video game enthusiasts and classroom instruction, and showcase the positive impact citizen science can have on research.

Use of Wearable Device Does Not Improve Weight Loss

Among overweight or obese young adults, the addition of a wearable technology device (that provided feedback on physical activity) to a standard behavioral intervention resulted in less weight loss over 24 months, according to a study appearing in the September 20 issue of JAMA. Effective long-term treatments are needed to address the obesity epidemic. There is wide availability of commercial technologies for physical activity and diet.

MRI Scanner Sees Emotions Flickering Across an Idle Mind

As you relax and let your mind drift aimlessly, you might remember a pleasant vacation, an angry confrontation in traffic or maybe the loss of a loved one. And now a team of researchers at Duke University say they can see those various emotional states flickering across the human brain.

Research News

A Step Forward in Building Functional Human Tissues

Mapping the 'Dark Matter' of Human DNA

Imaging Stroke Risk in 4D

Using Twitter as a Data Source for Studying Public Communication about Cardiovascular Health

Video Gamers Outdo Scientists in Contest to Discover Protein's Shape

Use of Wearable Device Does Not Improve Weight Loss

MRI Scanner Sees Emotions Flickering Across an Idle Mind

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