Virtual Reality Shows Promise in Fighting Depression

A new study published in JMIR Mental Health sheds light on the promising role of virtual reality (VR) in treating major depressive disorder (MDD). Titled "Examining the Efficacy of Extended Reality–Enhanced Behavioral Activation for Adults With Major Depressive Disorder: Randomized Controlled Trial," the research, led by Dr Margot Paul and team from Stanford University, unveiled the effectiveness of extended reality (XR)–enhanced behavioral activation (XR-BA) in easing symptoms of depression.

MDD affects millions worldwide, and access to evidence-based psychotherapies remains a challenge for many. Traditional treatments often face barriers, prompting researchers to explore innovative solutions. XR, which includes VR, encompasses various immersive technologies involving computer-generated environments that blend physical and digital worlds. Leveraging the immersive power of XR, this study explored XR-BA as a potential game-changer in MDD treatment.

Dr Paul and team conducted a randomized controlled trial among 26 outpatients with MDD receiving remote care. Using a VR Meta Quest 2 headset, the participants engaged in simulated pleasant or mastery activities, including playing a magical VR board game, deciphering clues to solve puzzles, dancing to music, and playing mini golf alone or with friends. Though the learning curve for using the headset was high, participants reported that the experience became more enjoyable and useful over time.

The results were comparable to traditional behavioral activation delivered via telehealth. Both XR-BA and traditional behavioral activation helped reduce the severity of depression in a significant way, as measured by the Patient Health Questionnaire–9. Moreover, the findings suggest that individuals in the XR-BA group might have experienced a heightened expectancy or placebo response because of the novelty of the technology and implicit beliefs regarding mental health treatment.

"These results indicate that XR may help to de-stigmatize mental healthcare and reduce barriers to individuals seeking care. Clinicians could use XR as a treatment tool to help motivate clients to actively participate in their psychotherapy treatment by completing ‘homework’ that is novel, fun, and accessible," remarked Dr Paul.

The study underscores the potential of VR, particularly XR-BA, in revolutionizing depression treatment by offering efficacy akin to traditional therapy. This is a promising avenue for enhancing treatment outcomes and addressing barriers to accessing evidence-based psychotherapies for MDD, potentially expanding care for affected individuals. Additionally, the exploration of XR's capacity to amplify placebo effects hints at the transformative possibilities of technology-assisted mental health therapies.

Paul M, Bullock K, Bailenson J, Burns D.
Examining the Efficacy of Extended Reality-Enhanced Behavioral Activation for Adults With Major Depressive Disorder: Randomized Controlled Trial.
JMIR Ment Health. 2024 Apr 15;11:e52326. doi: 10.2196/52326

Most Popular Now

Mobile Phone Data Helps Track Pathogen S…

A new way to map the spread and evolution of pathogens, and their responses to vaccines and antibiotics, will provide key insights to help predict and prevent future outbreaks. The...

AI Model to Improve Patient Response to …

A new artificial intelligence (AI) tool that can help to select the most suitable treatment for cancer patients has been developed by researchers at The Australian National University (ANU). DeepPT, developed...

Can AI Tell you if You Have Osteoporosis…

Osteoporosis is so difficult to detect in early stage it’s called the "silent disease." What if artificial intelligence could help predict a patient’s chances of having the bone-loss disease before...

Study Reveals Why AI Models that Analyze…

Artificial intelligence (AI) models often play a role in medical diagnoses, especially when it comes to analyzing images such as X-rays. However, studies have found that these models don’t always...

Think You're Funny? ChatGPT might b…

A study comparing jokes by people versus those told by ChatGPT shows that humans need to work on their material. The research team behind the study published on Wednesday, July 3...

Innovative, Highly Accurate AI Model can…

If there is one medical exam that everyone in the world has taken, it's a chest x-ray. Clinicians can use radiographs to tell if someone has tuberculosis, lung cancer, or...

New AI Approach Optimizes Antibody Drugs

Proteins have evolved to excel at everything from contracting muscles to digesting food to recognizing viruses. To engineer better proteins, including antibodies, scientists often iteratively mutate the amino acids -...

AI Speeds Up Heart Scans, Saving Doctors…

Researchers have developed a groundbreaking method for analysing heart MRI scans with the help of artificial intelligence (AI), which could save valuable NHS time and resources, as well as improve...

Researchers Customize AI Tools for Digit…

Scientists from Weill Cornell Medicine and the Dana-Farber Cancer Institute in Boston have developed and tested new artificial intelligence (AI) tools tailored to digital pathology - a rapidly growing field...

Young People Believe that AI is a Valuab…

Children and young people are generally positive about artificial intelligence (AI) and think it should be used in modern healthcare, finds the first-of-its-kind survey led by UCL and Great Ormond...