Virtual Patients and In Silico Clinical Studies Improve Blue Light Treatment for Psoriasis

A new study supports the use of virtual patients and in silico clinical studies to evaluate the effectiveness of blue light to reduce the symptoms of psoriasis. Researchers also demonstrated that this in silico approach can be used to improve the treatment response of patients with psoriasis to blue light by modifying the settings of the therapeutic protocol, as reported in the study published in Systems Medicine, an open access journal from Mary Ann Liebert, Inc., publishers. Click here to read the full article free on the Systems Medicine: Journal of Medical Systems Biology and Network Medicine website through September 5, 2019.

"In silico Clinical Studies on the Efficacy of Blue Light for Treating Psoriasis in Virtual Patients" was coauthored by Zandra FĂ©lix Garza, Peter Hilbers, and Natal van Riel, Eindhoven University of Technology, The Netherlands, and Joerg Liebmann and Matthias Born, Philips Electronics Netherlands BV, Eindhoven. The researchers note that the current computational model for studying the efficacy of blue light therapy only reproduces the response in the average patient in clinical trials and does not take into account individual variations amongst patients. Use of a computational model combined with a refined pool of virtual patients can adequately capture the patient variability in the response to treatment with blue light and the decrease in disease severity seen in previous clinical investigations. The authors suggest that a minimum of 2,500 virtual patients, which they refined down from an initial pool of 500,000 virtual patients, are needed to reproduce the responses seen in clinical investigations.

"This is a highly promising approach towards using statistical learning on virtual patient populations to draw actionable clinical conclusions on real patients, and thus a major step forward to precision medicine," says Co-Editor-in-Chief Prof. Dr. Jan Baumbach from Technical University of Munich.

Most Popular Now

App Determines COVID-19 Disease Severity…

A new mobile app can help clinicians determine which patients with the novel coronavirus (COVID-19) are likely to have severe cases. Created by researchers at NYU College of Dentistry, the...

NHS Trust Revolutionises Access to Menta…

North Staffordshire Combined Healthcare NHS Trust has selected the DXC Open Health Connect platform from DXC Technology (NYSE: DXC) and is creating a blueprint that could dramatically reduce mental health...

FDA Permits Marketing of First Game-Base…

The U.S. Food and Drug Administration (FDA) permitted marketing of the first game-based digital therapeutic device to improve attention function in children with attention deficit hyperactivity disorder (ADHD). The prescription-only...

HealthTunes Launches iOS App to Deliver …

HealthTunes has announceed the launch of the iOS App specifically created to help alleviate the mental health suffering of frontline healthcare workers. After months of fighting the pandemic, many frontline...

Philips Announces Collaboration with Ame…

Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, today announced it has once again joined forces with the American Telemedicine Association (ATA) to help further the...

Bluetooth Technology, the Best Ally to D…

"Tracers have been and are essential to manage the pandemic. Today, the tracing is done by hand and this work is slow and inaccurate. However, as we have seen, technology...

Successful Debut for DMEA sparks

16 - 18 June 2020, Berlin, Germany. DMEA sparks opened, featuring a wide range of topics. Federal Minister of Health Jens Spahn kicked off events. In his interview he focused on...

Digital Mental Health support to be Prov…

SilverCloud, the leading digital therapeutics provider, has partnered with mental health charity Northpoint Wellbeing to co-develop a new digital therapy programme to alleviate anxiety in young people. Coming at a...

Siemens Healthineers Offers Flexible Tel…

With its teamplay myCare Companion software, the company is bringing a new and flexible telemedicine solution to the market that enables remote care for patients with chronic diseases. The teamplay...

Siemens Healthineers Uses Artificial Int…

Siemens Healthineers introduces Ysio X.pree(1), the world's first intelligent X-ray system with integrated AI for optimizing the daily routine of image acquisition in radiography. To assist radiologists with the subsequent...

Computer Modelling Predicts where Vaccin…

Researchers have developed a model that can estimate regional disease burden and the impact of vaccination, even in the absence of robust surveillance data, a study in eLife reveals. The report...

Andrea Fiumicelli Appointed as a CEO of …

Dedalus Group, leader in Europe and one of the world's leading players in clinical and healthcare information systems supporting clinical professionals and healthcare facilities thanks to a wide portfolio of...