PASSPORT

In 2006, over 45.000 European citizens died of cirrhosis of the liver and 44,000 additional citizens of liver cancer, knowing that the same year 48,700 new liver cancer cases were declared. Surgical procedures remain the options that offer the foremost success rate against such pathologies. Regretfully, surgery is not so frequent due to several limitations.

Indeed, eligibility for liver surgery is based on the minimum safety liver volume remaining after resection (standardized FLR), but this minimum value varies over time and from one patient to another according to biological and mechanical properties of the liver. Since 1996, a large set of preoperative planning software has been developed, but all of them provide only the volume of the liver before and after resection. However interesting, this limited information is not sufficient to improve the rate of surgical eligibility.

PASSPORT for Liver Surgery (PAtient specific simulation and preoperative realistic training for liver surgery) project aims at overcoming these limitations by offering a patient-specific modelling that combines anatomical, mechanical, appearance and biological preoperative modelled information in a unified model of the patient. This first complete "Virtual liver" will be developed in an Open Source Framework allowing vertical integration of biomedical data, from macroscopic to microscopic patient information.

From these models, a dynamic liver modelling will provide the patient-specific minimum safety standardized FLR in an educative and preoperative planning simulator allowing to predict the feasibility of the gesture and surgeons' ability to realise it. Thus, any patient will be able to know the risk level of a proposed therapy.

The propsed project expects to increase the rate of surgical treatment so as to save patients with a liver pathology. To reach these purposes, PASSPORT is composed of a high level partnership between internationally renowned surgical teams, leading European research teams in surgical simulation and an international leading company in surgical instrumentation.

For further information, please visit:
http://www.passport-liver.eu

Project co-ordinator:
Institut de Recherche contre les Cancers de l'Appareil Digestif (France)

Partners:

  • Universität Leipzig (Germany)
  • Technischen Universität München (Germany)
  • University College London (United Kingdom)
  • Imperial College of Science, Technology and Medicine (United Kingdom)
  • Karl Storz GmbH & Co. KG (Germany)
  • Université Louis-Pasteur (France)
  • Institut National de Recherche en Informatique et en Automatique (France)
  • Eidgenössische Technische Hochschule Zürich (Switzerland)
  • Université catholique de Louvain (Belgium)

Timetable: from 06/2008 - to 05/2011

Total cost: € 5.460.000

EC funding: € 3.640.000

Programme Acronym: FP7-ICT

Subprogramme Area: Virtual physiological human

Contract type: Collaborative project (generic)

Most Popular Now

Orion Health Supports Professional Recor…

Orion Health is supporting the Professional Record Standards Body's partnership scheme by applying to become a 'quality partner'. The company, which is one of the UK’s leading providers of shared care...

FDA Authorizes Software that Can Help Id…

Today, the U.S. Food and Drug Administration authorized marketing of software to assist medical professionals who examine body tissues (pathologists) in the detection of areas that are suspicious for cancer...

Northumbria Healthcare Picks CliniSys to…

Pathologists at one of England's most innovative trusts have chosen the CliniSys laboratory information system (LIMS) as part of a digital strategy to support its drive to continually improve patient...

Study Finds Telemedicine Appointments Re…

Telemedicine appointments combined with in-person visits significantly reduced the risk of further illness for children with medically complex cases, according to results of a new study by researchers with The...

Contact-Tracing Apps could Improve Vacci…

Mathematical modeling of disease spread suggests that herd immunity could be achieved with fewer vaccine doses by using Bluetooth-based contact-tracing apps to identify people who have more exposure to others...

A Computer Algorithm Called 'Eva' May Ha…

A prescriptive computer program developed by the USC Marshall School of Business and Wharton School of Business of the University of Pennsylvania for Greece to identify asymptomatic, infected travelers...

FDA Clears First Major Imaging Device Ad…

Today, the U.S. Food and Drug Administration cleared the first new major technological improvement for Computed Tomography (CT) imaging in nearly a decade. "Computed tomography is an important medical imaging tool...

Using Internet in Retirement Boosts Cogn…

Using the internet during your retirement years can boost your cognitive function, a new study has found. Researchers from Lancaster University Management School, the Norwegian University Science and Technology and...

AI Tool Improves Accuracy of Breast Canc…

A computer program trained to see patterns among thousands of breast ultrasound images can aid physicians in accurately diagnosing breast cancer, a new study shows. When tested separately on 44,755 already...

Study Shows Trust is still at Heart of N…

A new study has shown that issues surrounding trust are still at the heart of people's reluctance to download and use the NHS App, particularly among Black, Asian and minority...

Time until Dementia Symptoms Appear can …

Researchers at Washington University School of Medicine in St. Louis have developed an approach to estimating when a person who is likely to develop Alzheimer’s disease, but has no cognitive...