Researchers Outline in Science How Brain Research Makes New Demands on Supercomputing

"Understanding the brain in all its complexity requires insights from multiple scales - from genomics, cells and synapses to the whole-organ level. This means working with large amounts of data, and supercomputing is becoming an indispensable tool to tackle the brain," says Katrin Amunts, Scientific Director of the Human Brain Project (HBP), Director of the C. and O. Vogt-Institute of Brain Research, Universitätsklinikum Düsseldorf and Director of the Institute of Neuroscience and Medicine (INM-1) at Research Centre Jülich.

"It's an exciting time in supercomputing," says Thomas Lippert, Director of the Jülich Supercomputing Centre and leader of supercomputing in the Human Brain Project. "We get a lot of new requests from researchers of the neuroscience community that need powerful computing to tackle the brain's complexity. In response, we are developing new tools tailored to investigating the brain."

The human brain contains around 86 billion neurons that form trillions of contact points. Imaging an entire brain at cellular resolutions produces data in the range of several Petabytes; electron microscopy of a whole brain would amount to more than one Exabyte of data. "Brain research, medicine and information technologies face challenges that can only be addressed by joining the forces of all three domains," says Amunts.

In Europe, the big data challenge of neuroscience is addressed by the Human Brain Project’s research infrastructure EBRAINS. It provides a range of tools, data-, and compute-services to brain researchers. This includes access to supercomputing systems via the Fenix federated Infrastructure, which has been set up by Europe’s leading Supercomputing Centres as part of the Human Brain Project and will serve communities beyond brain research.

Within the next five years, Europe is aiming to deploy its first two exascale supercomputers. They will be acquired by the European High Performance Computing Joint Undertaking (EuroHPC JU), a joint initiative between the EU, European countries and private partners. "The brain research community stands ready to use these exascale systems," says Amunts.

Katrin Amunts, Thomas Lippert.
Brain research challenges supercomputing.
Science, 2021. doi: 10.1126/science.abl8519

Most Popular Now

New App may Help Caregivers of People Ge…

A new study by investigators from Mass General Brigham showed that a new app they created can help improve the quality of life for caregivers of patients undergoing bone marrow...

Philips Foundation 2024 Annual Report: E…

Marking its tenth anniversary, Philips Foundation released its 2024 Annual Report, highlighting a year in which the Philips Foundation helped provide access to quality healthcare for 46.5 million people around...

New AI Transforms Radiology with Speed, …

A first-of-its-kind generative AI system, developed in-house at Northwestern Medicine, is revolutionizing radiology - boosting productivity, identifying life-threatening conditions in milliseconds and offering a breakthrough solution to the global radiologist...

Scientists Argue for More FDA Oversight …

An agile, transparent, and ethics-driven oversight system is needed for the U.S. Food and Drug Administration (FDA) to balance innovation with patient safety when it comes to artificial intelligence-driven medical...

New Research Finds Specific Learning Str…

If data used to train artificial intelligence models for medical applications, such as hospitals across the Greater Toronto Area, differs from the real-world data, it could lead to patient harm...

Giving Doctors an AI-Powered Head Start …

Detection of melanoma and a range of other skin diseases will be faster and more accurate with a new artificial intelligence (AI) powered tool that analyses multiple imaging types simultaneously...

Patients say "Yes..ish" to the…

As artificial intelligence (AI) continues to be integrated in healthcare, a new multinational study involving Aarhus University sheds light on how dental patients really feel about its growing role in...

AI Agents for Oncology

Clinical decision-making in oncology is challenging and requires the analysis of various data types - from medical imaging and genetic information to patient records and treatment guidelines. To effectively support...

'AI Scientist' Suggests Combin…

An 'AI scientist', working in collaboration with human scientists, has found that combinations of cheap and safe drugs - used to treat conditions such as high cholesterol and alcohol dependence...

Brains vs. Bytes: Study Compares Diagnos…

A University of Maine study compared how well artificial intelligence (AI) models and human clinicians handled complex or sensitive medical cases. The study published in the Journal of Health Organization...

Start-ups in the Spotlight at MEDICA 202…

17 - 20 November 2025, Düsseldorf, Germany. MEDICA, the leading international trade fair and platform for healthcare innovations, will once again confirm its position as the world's number one hotspot for...