Bayer and Exscientia Collaborate to Leverage the Potential of Artificial Intelligence in Cardiovascular and Oncology Drug Discovery

BayerBayer and Exscientia Ltd., a UK-based Artificial Intelligence (AI)-driven drug discovery company, have entered into a three-year, multi-target collaboration. The partners will work on early research projects combining Exscientia's proprietary AI drug discovery platform and drug design know-how with Bayer's data and drug discovery capabilities. They aim to identify and optimize novel lead structures for potential drug candidates to treat cardiovascular and oncological diseases. Exscientia may be eligible to receive up to EUR 240 million, including upfront and research payments, near term and clinical milestones. As part of the agreement, Exscientia may also receive sales royalties. Bayer owns the rights to novel lead structures generated as part of the collaboration.

AI has the potential to accelerate drug discovery and improve the drug development productivity in terms of quality, cost and cycle time. Up to now, it takes 12 to 15 years from early research to marketing approval of a new drug. The collaboration focuses on early stage research by using an AI-based algorithm to predict potential drug molecules. Exscientia's AI-driven drug discovery technology provides novel chemical matter for difficult-to-address targets and could identify novel drug candidates more efficiently through less optimization cycles.

"We are driving forward digital transformation in R&D as we believe that digital technologies such as AI can simplify and speed up the discovery and development of new drugs for patients," said Dr. Joerg Moeller, Member of the Executive Committee of Bayer AG's Pharmaceuticals Division and Head of Research and Development. "The collaboration with Exscientia is expected to help us to achieve project milestones earlier and at the same time accelerate timelines by enabling more precise identification of suitable drug targets and lead structures."

"We're delighted to collaborate with Bayer, a globally recognized pharmaceutical company who has already committed significant investment to treating challenging diseases," said Professor Andrew Hopkins, CEO of Exscientia. "Since our pioneering Nature papers demonstrated the automated design of small-molecules, we have enhanced our platform and exemplified it commercially, by accelerating the discovery of future drug molecules with partners. We’re excited to now work with Bayer researchers to drive this transformational change in key therapeutic areas."

The Pharmaceuticals Business Development & Licensing team of Bayer facilitated this collaboration.

About artificial intelligence at Bayer Pharmaceuticals

Artificial intelligence provides significant opportunities for Bayer's Pharmaceuticals business. Bayer is committed to realizing the potential value associated with big data, advanced analytics, and artificial intelligence, as it continues to explore and leverage them along the value chain. Bayer believes that there are three ways that artificial intelligence could be applied in our business: to strengthen and accelerate innovation, to advance operations and to identify new business opportunities. Such technologies could therefore support Bayer in getting the right treatment to the right patient at the right time, more efficiently and faster than we do today.

About Exscientia

Exscientia is at the forefront of Artificial Intelligence (AI)-driven drug discovery and design. By fusing the power of AI with the discovery experience of seasoned drug hunters, Exscientia is the first company to automate drug design, surpassing conventional approaches.

About Bayer

Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition. Its products and services are designed to benefit people by supporting efforts to overcome the major challenges presented by a growing and aging global population. At the same time, the Group aims to increase its earning power and create value through innovation and growth. Bayer is committed to the principles of sustainable development, and the Bayer brand stands for trust, reliability and quality throughout the world. In fiscal 2018, the Group employed around 117,000 people and had sales of 39.6 billion euros. Capital expenditures amounted to 2.6 billion euros, R&D expenses to 5.2 billion euros.

Most Popular Now

IBM Watson Health Recognizes Top-Perform…

IBM (NYSE: IBM) Watson Health® announced its 2020 Fortune/IBM Watson Health 100 Top Hospitals list and 15 Top Health Systems award winners, naming the top-performing hospitals and health systems in...

Chatbots can Ease Medical Providers' Bur…

COVID-19 has placed tremendous pressure on health care systems, not only for critical care but also from an anxious public looking for answers. Research from the Indiana University Kelley School...

Abbott Receives FDA Approval for New Hea…

Abbott (NYSE: ABT) announced that the U.S. Food and Drug Administration (FDA) has approved the company's next-generation Gallant™ implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy defibrillator (CRT-D) devices. The...

The New Tattoo: Drawing Electronics on S…

One day, people could monitor their own health conditions by simply picking up a pencil and drawing a bioelectronic device on their skin. In a new study, University of Missouri...

Towards an AI Diagnosis Like the Doctor…

Artificial intelligence (AI) is an important innovation in diagnostics, because it can quickly learn to recognize abnormalities that a doctor would also label as a disease. But the way that...

SARS-CoV-2 Antibody Test from Siemens He…

Public Health England, in partnership with the University of Oxford, recently conducted a head-to-head evaluation of four commercial immunoassay tests available in the UK and used for the detection of...

Researchers Develop Software to Find Dru…

Washington State University researchers have developed an easy-to-use software program to identify drug-resistant genes in bacteria. The program could make it easier to identify the deadly antimicrobial resistant bacteria that...

Philips Introduces First-of-a-Kind Mobil…

Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, today announced it introduced first-of-its-kind mobile Intensive Care Units (ICUs) in India. Designed to meet the critical-care requirements...

Proposed Framework for Integrating Chatb…

While the technology for developing artificial intelligence-powered chatbots has existed for some time, a new viewpoint piece in JAMA lays out the clinical, ethical, and legal aspects that must be...

Clinical-Grade Wearables Offer Continuou…

Although it might be tempting to rely on your fitness tracker to catch early signs of COVID-19, Northwestern University researchers caution that consumer wearables are not sophisticated enough to monitor...

World's Smallest Imaging Device has Hear…

A team of researchers led by the University of Adelaide and University of Stuttgart has used 3D micro-printing to develop the world's smallest, flexible scope for looking inside blood vessels...

Optimizing Neural Networks on a Brain-In…

Many computational properties are maximized when the dynamics of a network are at a "critical point", a state where systems can quickly change their overall characteristics in fundamental ways, transitioning...