The business environment and sustainable business models for eHealth SMEs have been a major challenge when introducing innovations in new healthcare delivery. The scope is co-ordinating post R&D and offering support for developing business models, improving the maturity of the new products emerging from Europe's leading Health ICT SMEs, developing a pro-innovation approach to address legal conditions in Europe and globally on a case-by-case basis.

The dedicated SME instrument's supports close-to-market activities, with the aim to give a strong boost to breakthrough innovation. Highly innovative SMEs with a clear commercial ambition and a potential for high growth and internationalisation are the prime target.

In a global perspective Europe can gain from effective knowledge-based decision-making, widening its knowledge base beyond science, not the least with regard to science, technology and innovation (STI) governance itself.

Evidence from Sixth Framework Programme Science and Society (S&S) and Seventh Framework Programme Science in Society (SiS) programmes shows that more consistent policy development in Science and Technology requires systematic cooperation and a shared knowledge base on which European, national and sub-national research and innovation policy decisions can be drawn from.

The Innovative Medicines Initiative (IMI) has launched its 5th Call for proposals under the IMI 2 programme. IMI 2 - Call 5 has a total budget of €95 million and features 6 topics. Of these, four focus on different aspects of Alzheimer's disease, one focuses on diabetic kidney disease, and one addresses patient input on assessments of the benefits and risks of medicines.

Supporting a large set of early stage, high risk visionary science and technology collaborative research projects is necessary for the successful exploration of new foundations for radically new future technologies. Nurturing fragile ideas requires an agile, risk-friendly and highly interdisciplinary research approach, expanding well beyond the strictly technological disciplines.

The Type 1 Diabetes Program of The Leona M. and Harry B. Helmsley Charitable Trust has announced the launch of the Diabetes Data Innovation Initiative. The Trust has issued a request for proposals to identify high-potential projects and pioneering digital health solutions that could enable the integration of diabetes data to identify trends and develop personalized patient guidance and decision support for providers.

Mixed consortia of robot manufacturers and research institutes have the opportunity to apply for a total funding of 1.2 million Euros in a competitive process in order to develop small-scale test series as solutions for the given challenge. AQuAS (Agència de Qualitat I Avaluació Sanitàries de Catalunya), a public entity of the Catalan Department of Health, and Fundació Privada Sant Antoni Abat, a non-profit private foundation managing and developing innovation and research in healthcare, have defined the Comprehensive Geriatric Assessment (CGA) challenge.

The 2015 Call Challenge of the AAL Programme aims to fund ICT based innovative, transnational and multi-disciplinary collaborative projects with a clear market orientation that support older adults to live:

A series of calls in Horizon 2020 under Societal Challenge "Health, demographic change and wellbeing" with relevance to ICT for Health (eHealth) are now open: PHC-21-2015, PHC-25-2015, PHC-27-2015, PHC-28-2015, PHC-29-2015, PHC-30-2015.