In the study, published January 28, 2023 in Nature Communications, researchers used the approach to identify a new antibody that binds a major cancer target 17-fold tighter than an existing antibody drug.
The Leona M. and Harry B. Helmsley Charitable Trust has awarded OHSU more than $4.3 million to support this work.
For many types of cancer, early detection can lead to better outcomes for patients. While scientists are developing new blood tests that analyze DNA to aid in earlier detection, these new technologies have limitations, including cost and sensitivity.