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Drug Toxicity Predicted by Differences Between Preclinical Models and Humans

In the UK, there was a case where TGN1412, an immunotherapy under development, triggered a cytokine storm within hours of administration to humans, leading to multiple organ failure. Another example, Aptiganel, a stroke drug candidate, was also highly effective in animals but was discontinued in humans due to side effects such as hallucinations and sedation.

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AXREM and Highland Extend Partnership to Drive Growth and Visibility for the UK's Diagnostic Health Tech Sector

UK trade association AXREM and health tech growth specialist Highland have extended their partnership for two further years, reaffirming a shared commitment to supporting growth across the UK’s diagnostic and health technology markets.

AXREM represents member companies that collectively provide the majority of diagnostic medical imaging and radiotherapy equipment used in UK hospitals.

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AI Can Speed Antibody Design to Thwart Novel Viruses

Artificial intelligence (AI) and "protein language" models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional study led by researchers at Vanderbilt University Medical Center.

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How Mayo Clinic Experts Are Using AI to Better Detect Sleep Apnea, Especially in Women

Mayo Clinic researchers have developed an artificial intelligence (AI) algorithm that can identify obstructive sleep apnea (OSA) using the results from an electrocardiogram (ECG) - a common heart test. The innovation could make it faster, cheaper, and easier to spot sleep apnea, particularly in women, who are often underdiagnosed.

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Team's Biosensor Technology may Lead to Breath Test for Lung Cancer

University of Texas at Dallas researchers have developed biosensor technology that when combined with artificial intelligence (AI) shows promise for detecting lung cancer through breath analysis.

The electrochemical biosensor identifies eight volatile organic compounds (VOCs) that are potential biomarkers for thoracic cancers, which include lung and esophageal cancers.

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New Method for Intentional Control of Bionic Prostheses

Despite enormous progress in the past two decades, the intentional control of bionic prostheses remains a challenge and the subject of intensive research. Now, scientists at the Medical University of Vienna and Imperial College London have developed a new method for precisely detecting the nerve signals remaining after an arm amputation and utilising them to control an artificial arm.

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Generative AI could be Transformative in Mental Health Care

New work by a University of Illinois Urbana-Champaign scholar harnesses the power of generative artificial intelligence, using it in tandem with measurement-based care and access-to-care models in a simulated case study, creating a novel framework that promotes personalized mental health treatment, addresses common access barriers and improves outcomes for diverse individuals.

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The First App for Selecting the Most Effective AI Models for Treatment of an Individual Organ

A team from the Department of Electronics, Information and Bioengineering of the Politecnico di Milano, led by dr. Andrea Moglia, has developed the first online application that helps us understand which Artificial Intelligence model is best suited to create 3D images of every individual organ. This makes treatment of the patient more accurate and reliable.

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Making Cancer Vaccines More Personal

In a new study, University of Arizona researchers created a model for cutaneous squamous cell carcinoma, a type of skin cancer, and identified two mutated tumor proteins, or neoantigens, that contain features of good candidates for a vaccine. At the same time, they used artificial intelligence to create 3D models to help them understand and predict which neoantigens could provoke T cells, a type of white blood cell critical to the immune system, to attack the cancer.

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AI Tool Beats Humans at Detecting Parasites in Stool Samples

Scientists at ARUP Laboratories have developed an artificial intelligence (AI) tool that detects intestinal parasites in stool samples more quickly and accurately than traditional methods, potentially transforming how labs diagnose parasitic infections around the world.

Identifying parasites under the microscope has long been a painstaking task requiring highly trained experts to manually scour each sample for telltale cysts, eggs or larva.

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